https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 Low-dose versus standard-dose intravenous alteplase in acute ischemic stroke https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:24860 Thu 27 Jan 2022 15:58:04 AEDT ]]> Tenecteplase versus alteplase before thrombectomy for ischemic stroke https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:32925 Thu 17 Mar 2022 14:40:19 AEDT ]]> Pioglitazone after ischemic stroke or transient ischemic attack https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:24617 Thu 17 Feb 2022 09:26:56 AEDT ]]> Estimated GFR and the effect of intensive blood pressure lowering after acute intracerebral hemorrhage https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:27846 90, 60-90, and <60 mL/min/1.73 m², respectively). Outcomes: The effect of admission eGFR on the primary outcome of death or major disability at 90 days (defined as modified Rankin Scale scores of 3-6) was analyzed using a multivariable logistic regression model. Potential effect modification of intensive BP lowering treatment by admission eGFR was assessed by interaction terms. Results: Of 2,623 included participants, 912 (35%) and 280 (11%) had mildly and moderately/severely decreased eGFRs, respectively. Patients with moderately/severely decreased eGFRs had the greatest risk for death or major disability at 90 days (adjusted OR, 1.82; 95% CI, 1.28-2.61). Effects of early intensive BP lowering were consistent across different eGFRs (P = 0.5 for homogeneity). Limitations: Generalizability issues arising from a clinical trial population. Conclusions: Decreased eGFR predicts poor outcome in acute ICH. Early intensive BP lowering provides similar treatment effects in patients with ICH with decreased eGFRs.]]> Thu 09 Dec 2021 11:03:39 AEDT ]]> Significance of perihematomal edema in acute intracerebral hemorrhage: the INTERACT trial https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:7411 Sat 24 Mar 2018 08:42:44 AEDT ]]> Interprofessional, practice-driven research: reflections of one 'community of inquiry' based in acute stroke https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:7389 Sat 24 Mar 2018 08:40:12 AEDT ]]> Baseline diabetic status and admission blood glucose were poor prognostic factors in the EPITHET trial https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:9556 Sat 24 Mar 2018 08:34:49 AEDT ]]> Acute ischemic stroke: imaging-guided tenecteplase treatment in an extended time window https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:7143 Sat 24 Mar 2018 08:34:14 AEDT ]]> Imaging the penumbra: strategies to detect tissue at risk after ischemic stroke https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:7969 Sat 24 Mar 2018 08:33:40 AEDT ]]> Time to treatment with intravenous alteplase and outcome in stroke: an updated pooled analysis of ECASS, ATLANTIS, NINDS, and EPITHET trials https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:10429 Sat 24 Mar 2018 08:13:15 AEDT ]]> Ischemic diffusion lesion reversal is uncommon and rarely alters perfusion-diffusion mismatch https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:10750 Sat 24 Mar 2018 08:08:22 AEDT ]]> Perfusion computed tomography thresholds defining ischemic penumbra and infarct core: studies in a rat stroke model https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:21852 Sat 24 Mar 2018 07:55:30 AEDT ]]> Endovascular therapy for ischemic stroke with perfusion-imaging selection https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:27444 Sat 24 Mar 2018 07:32:37 AEDT ]]>